Understanding, Managing, and Living Beyond Testicular Cancer

What is Testicular Cancer?

Testicular cancer develops in one or both testicles, the male reproductive glands responsible for producing sperm and testosterone. Although it is relatively rare compared to other cancers, it is the most common cancer in young men aged 15–35.

The majority of testicular cancers begin in germ cells, the cells that produce sperm. These are classified as:

  • Seminomas – grow more slowly and are sensitive to radiation.

  • Non-seminomas – tend to grow faster and spread earlier.

With early detection and treatment, testicular cancer has one of the highest survival rates among all cancers.

Signs and Symptoms of Testicular Cancer

Recognizing symptoms early can lead to effective treatment. Common signs include:

A lump or swelling in either testicle (often painless)

A feeling of heaviness in the scrotum

Dull ache or pain in the lower abdomen, back, or groin

Sudden collection of fluid in the scrotum

Discomfort or pain in the testicle or scrotum

Enlargement or tenderness of the breasts (rare, due to hormonal changes)

If you notice any changes in your testicles, it is important to see a doctor immediately.

Diagnosis of Testicular Cancer

Accurate diagnosis is vital for treatment planning. Common tests include:

Medical History & Physical Exam

Checks for lumps, swelling, or tenderness in the testicles.

Ultrasound of the Testicles

Uses sound waves to distinguish between cancerous and non-cancerous lumps.

Blood Tests (Tumor Markers)

Measures levels of specific proteins (AFP, HCG, LDH) linked to testicular cancer.

Surgery (Orchiectomy)

Removal of the affected testicle is often the first step to confirm diagnosis.

Imaging Tests (CT or MRI scans)

Check for cancer spread to lymph nodes or other organs.

Staging is critical to guide treatment decisions and predict outcomes.

Treatments for Testicular Cancer

Treatment depends on the type (seminoma or non-seminoma), stage, and overall health. Options include:

Surgery

The primary treatment, often involving removal of the affected testicle (radical inguinal orchiectomy).

Radiation Therapy

Mainly used for seminomas; high-energy rays kill cancer cells in lymph nodes.

Chemotherapy

Effective for both seminomas and non-seminomas, especially if cancer has spread.

Stem Cell Transplant

Used in rare, advanced cases after high-dose chemotherapy.

Most men with testicular cancer respond very well to treatment, and cure rates are high.

Managing Side Effects

Treatment can cause side effects, which vary depending on the method used.

Common side effects may include:

Tips to manage side effects:

Communication with your healthcare team ensures safe management of side effects.

Living With & Beyond Testicular Cancer

Life after treatment often brings physical and emotional adjustments.

Helpful strategies include:

These steps support recovery and long-term health.

Children & Young People

Although rare, testicular cancer can affect adolescents.

Key considerations include:

Early support helps young patients cope with treatment and recovery.

End-of-Life Care

For advanced cases that don’t respond to treatment, care focuses on comfort and quality of life.

Core aspects of care include:

The goal is dignity, symptom relief, and emotional well-being.
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